Tetrabutylammonium Hydroxide CAS 2052-49-5
Tetrabutylammonium Hydroxide CAS 2052-49-5 With Good Service
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Name: Tetrabutylammonium Hydroxide
CAS: 2052-49-5
MOQ: 1KG
Directory Guidance on Tetrabutylammonium Hydroxide
Chemical Structure
Basic Info:
| Melting point | 27-30 °C(lit.) |
| Boiling point | 100 °C |
| density | 0.995 |
| vapor density | 1 (vs air) |
| vapor pressure | 2.3 kPa (@ 20°C) |
| refractive index | 1.4 |
| Fp | 7°C |
Product Introduction:
Tetrabutylammonium Hydroxide TBAOH or TBAH is a commonly used organic hydroxide with the chemical formula C16H37NO. Tetrabutylammonium hydroxide is soluble in water and polar solvents, such as methanol, and its aqueous solution is alkaline, with a pH value close to 14. It is sensitive to air and moisture, so it needs to be sealed and kept in cool and dry conditions when stored.
Chemically, Tetrabutylammonium Hydroxide is a strong alkaline substance that can neutralize with acid to produce the corresponding salt. It is more alkaline than inorganic hydroxides such as sodium hydroxide, so it is widely used as an alkaline catalyst in organic synthesis.
Tetrabutylammonium Hydroxide can also be used as a deprotonator in some reactions to promote the conduct of some organic reactions, such as esterification and nucleophilic substitution reactions. It is also able to efficiently form complexes with certain metal ions and can be used for extraction or separation of metal ions in some cases.
Tetrabutylammonium Hydroxide has a variety of applications in the laboratory and industry. For example, in high performance liquid chromatography (HPLC), it is used as a reagent to separate and analyze organic compounds. In addition, it also plays an important role in synthetic chemistry, especially in the synthesis of some polymer compounds and organic synthesis, can be used as a catalyst or regulator.
Although Tetrabutylammonium Hydroxide has important uses in many chemical processes, it requires special care when handled due to its strong alkalism and corrosiveness on the skin. When stored, it should be kept in an airtight container and avoid contact with water or moisture, as moisture may cause it to decompose. During use, be sure to wear appropriate protective equipment, such as gloves, goggles and protective clothing to ensure safety.
Nature and Specifications:
| Item | Specification |
| Product Name | Tetrabutylammonium Hydroxide |
| CAS No. | 2052-49-5 |
| Appearance | Liquid |
| Shelf Life | 2 years |
| Packing | As your requirements |
| storage temp. | Store below +30°C. |
| solubility | Miscible with organic solvents. |
| form | Solution |
| Specific Gravity | 0.8586 |
| color | APHA: ≤30 |
| Odor | Odorless |
Product service:
- Certificate Of Analysis (COA)
- Material Safety Data Sheet (MSDS)
- Route of synthesis (ROS)
- Method of Aanlysis (MOA)
- Nuclear Magnetic Resonance (NMR)
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Tetrabutylammonium Hydroxide, more commonly referred to as TBHO, finds applications across many fields due to its strong alkalinity, solubility and superior catalytic properties. As such, TBHO plays an essential part in chemical synthesis, material science research, environmental protection efforts and many other applications.
Tetrabutylammonium Hydroxide, as a strong alkaline reagent, has long been used in organic chemistry as an alkaline catalyst and deprotonation agent, with applications including chemical synthesis.
As an alkaline catalyst, potassium hydroxide can accelerate nucleophilic substitution reactions, esterification reactions and hydrogenation reactions in molecules. By effectively eliminating protons from molecules’ surfaces, it accelerates reactions between nucleophiles and substrates in molecules. Furthermore, deprotonation agents such as potassium hydroxide may be used as deprotonation agents during organic reactions involving negatively charged species generation; such applications include reactions such as olefins cyclization reactions and alcohol etherification reactions.
Additionally, it also plays an essential role in some complex organic syntheses, including aromatic compound synthesis, pharmaceutical intermediate production, and fine chemical manufacture.
2. Ionic Liquids and Metal Complexation
Tetrabutylammonium Hydroxide can not only act as a catalyst in organic chemical reactions, but it can also play an active role in metal ion complexation reactions used for separation, extraction and synthesis. Incorporating complexes with metal ions (copper, iron etc), TBH forms complexes with some that form copper-iron complexes which has many applications including extraction catalysis.
Tetrabutylammonium Hydroxide can form ionic liquids when mixed with solvents, providing important applications in chemical reactions, separation technologies and other fields. Ionic liquids help improve selectivity and reaction rate of reactions while improving reaction efficiency. When present together with Tetrabutylammonium Hydroxide it can further optimize selectivity and rate thereby optimizing reaction efficiency.
3. Environmental Protection and Wastewater Treatment
Tetrabutylammonium Hydroxide plays an integral part in environmental protection, particularly wastewater treatment and removal of harmful substances from wastewater streams. As a powerful alkaline chemical reagent it neutralizes acidic substances present in wastewater while simultaneously adjusting its pH value accordingly.
Tetrabutylammonium Hydroxide can play an invaluable role in treating industrial wastewater and waste gas after adsorption, by helping remove harmful metal ions (including heavy metals) via precipitation with metal ions. Furthermore, its reaction with wastewater containing organic acids or amino acids precipitates their respective salts precipitating out, further decreasing concentration of harmful substances while contributing to purification and recycling of the water body.
4. Application in High Performance Liquid Chromatography (HPLC)
Tetrabutylammonium Hydroxide has many uses in analytical chemistry, particularly high performance liquid chromatography (HPLC). When included as part of the mobile phase for HPLC analysis of polar compounds or organic acids, its presence can enhance separation efficiency for better separation of analytes.
As an ion pair reagent, it can also be used to alter the charge state of analytes and enhance their interaction with a chromatographic column for improved separation efficiency and resolution; making it especially suitable for separating charged or highly polar compounds.
5. Materials Science and Synthesis
Within materials science, Tetrabutylammonium Hydroxide plays a critical role in the creation of certain specific materials such as nanomaterials and polymers. This reagent acts as a catalyst to speed up certain nanoparticle synthesis reactions; by changing reaction conditions accordingly, its size and morphology can be tailored. As an auxiliary reagent it plays an integral part in producing carbon nanotubes and metal nanoparticles among others.
6. Biomedicine
While Tetrabutylammonium Hydroxide may only be occasionally utilized in biomedicine, its versatility in certain biochemical reactions makes it useful. For instance, it can adjust pH values, promote enzyme reactions or boost catalytic efficiency during certain biocatalytic reactions. Likewise, drug synthesis requires strong alkaline conditions; Tetrabutylammonium Hydroxide could serve as a catalyst or intermediate during drug synthesis process.
1.Strong Basicity
Tetrabutylammonium Hydroxide has an exceptionally strong basicity that enables it to perform superb catalysis for many chemical reactions, including organic synthesis, transesterification and deprotonation processes. Furthermore, its strong basicity enables it to remove protons (H+) while stimulating reaction.
2.High solubility
Solubletiennent Tetrabutylammonium Hydroxide exhibits excellent solubility in water and alcohol solvents, making it suitable for use with various solvents to form stable solutions that meet different reaction conditions. Furthermore, its solubility allows it to demonstrate higher efficiency during liquid phase reactions such as catalytic ones that facilitate reactant conversion.
3. Phase Transfer Catalyst
Tetrabutylammonium Hydroxide acts as a phase transfer catalyst to promote the movement of nucleophiles between aqueous and organic phases, making it particularly useful in organic synthesis for nucleophilic substitution, hydrogenation and esterification reactions which increase reaction rates, yields and by-product reduction while simultaneously decreasing reaction by-product formation. This property makes TBH an invaluable ally in organic production processes such as nucleophilic substitution, hydrogenation and esterification reactions as it promotes transfer between nucleophile-rich environments as it facilitates nucleophilic substitution reactions which reduce reaction by-product formation while simultaneously increasing reaction rates and yields while simultaneously decreasing reaction by-product formation by up to an order of magnitude of 10 times over its use in this application alone!
4. Complexing ability with metal ions
Tetrabutylammonium Hydroxide’s ability to form complexes with various metal ions has made it widely utilized for metal extraction, catalytic reactions and metal ion separation applications. For instance, its composition allows it to react with transition metal ions such as copper, iron etc. in catalytic reactions by creating soluble complexes which increase activity during catalysis processes.
5. Stable Catalytic Performance
Tetrabutylammonium Hydroxide offers excellent catalytic properties and functions across a broad temperature and pH range, even under challenging reaction conditions (including high temperature/strong alkaline environments) such as high temperature reactions with strong acidification reactions requiring TBAOH as the catalyst. As such, its catalytic performance remains excellent even under such challenging circumstances, improving selectivity and yield in reactions utilizing it as the catalyst.
6. Low Toxicity and Good Safety
Tetrabutylammonium Hydroxide stands out among other strongly alkaline substances by being relatively nontoxic and safe when in use, with milder levels of toxicity and corrosion potential than its competitors, making it suitable for many industries that wish to decrease environmental pollution while improving process safety.
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Related References:
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