Phenoxyethanol CAS 122-99-6


Factory wholesale Diglycerol CAS 627-82-7 With Free Sample
- Appearance:Liquid
- Purity:99.8%
- Delivery:30days
- Sample Available:Available
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Name: Phenoxyethanol
CAS: 122-99-6
MOQ: 1KG
Directory Guidance on Phenoxyethanol
Chemical Structure
Basic Info:
Melting point | 11-13 °C (lit.) |
Boiling point | 247 °C (lit.) |
density | 1.102 g/mL at 25 °C (lit.) |
vapor density | 4.8 (vs air) |
vapor pressure | 0.01 mm Hg ( 20 °C) |
refractive index | n20/D 1.539 |
Product Introduction:
Phenoxyethanol, also known as phenoxyethanol, ethylene glycol phenyl ether, etc., is an organic synthetic compound with a chemical formula of C₈H₁₀O₂. It is a colorless, slightly viscous liquid with a slight fragrance and astringency. It can be dissolved in water and can be mixed with acetone, ethanol, glycerol and other substances at will. In terms of chemical structure, Phenoxyethanol belongs to aromatic ether alcohol compounds. Its molecular structure gives it unique physical and chemical properties, making it widely used in many fields.
There are many main methods for the production process of Phenoxyethanol, among which the phenol-ethylene oxide method is a more common preparation method. This method uses phenol and ethylene oxide as the main raw materials, reacts in an alkaline medium, and finally generates Phenoxyethanol after a series of chemical treatments. In addition, there are different synthetic routes such as the phenol-chloroethanol method and the phenoxyacetic acid reduction method. Different preparation methods may have certain differences in reaction conditions, catalyst use and product purity. Enterprises will choose the appropriate production process based on their own technical strength and cost control factors.
From a toxicological point of view, Phenoxyethanol is a low-toxic substance, with an oral LD50 of 3000 mg/kg for rats and 4000 mg/kg for mice. This means that at normal concentrations, the toxicity risk of Phenoxyethanol to the human body is relatively low, which is an important reason why it can be widely used in products that come into direct contact with the human body.
Nature and Specifications:
Item | Specification |
Product Name | Phenoxyethanol |
CAS No. | 122-99-6 |
Appearance | Liquid |
Shelf Life | 2 years |
Packing | As your requirements |
Fp | >230 °F |
storage temp. | Store below +30°C. |
solubility | soluble, clear, colorless to very faintly yellow |
pka | 14.36±0.10(Predicted) |
form | Liquid |
color | Clear colorless |
Specific Gravity | 1.109 (20/4℃) |
Product service:
- Certificate Of Analysis (COA)
- Material Safety Data Sheet (MSDS)
- Route of synthesis (ROS)
- Method of Aanlysis (MOA)
- Nuclear Magnetic Resonance (NMR)
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- Free Sample
- Factory audit
Phenoxyethanol is an extremely popular cosmetic ingredient and an integral component in many skincare formulations. As a preservative, it serves mainly as an effective defense against bacteria, fungi and yeast growth; therefore extending shelf life, protecting products from degradation due to contamination by microbes, and protecting consumers. Phenoxyethanol has many applications within cosmetics products such as lotions, moisturizing creams, essences, sunscreens and toners; serving both as an antioxidant and preservative agent.
In the pharmaceutical industry, Phenoxyethanol also has important application value. It is used to produce a variety of drugs, including drugs for Pseudomonas aeruginosa otitis media, anesthetics, vaccines, antibacterial drugs, and skin infection drugs. Among these drugs, Phenoxyethanol mainly plays an antibacterial, anti-inflammatory and inhibitory role in the central nervous system. For example, in vaccines, Phenoxyethanol can be used as a preservative ingredient to ensure the stability of vaccines during storage and use, and prevent microbial contamination from affecting the effectiveness and safety of vaccines;
Phenoxyethanol has an indispensable place in the chemical industry. As an excellent solvent that dissolves many organic substances, Phenoxyethanol finds use across paints, inks, ballpoint pen oils and other industries. Phenoxyethanol can be used as both a solvent and modifier during paint production to enhance fluidity, adhesion and protective film coverage of painted objects; similarly for ink production it serves both viscosity adjustment and color expression, providing quality printing products and durability assurance for printed goods.
Phenoxyethanol has many uses within the food processing industry. While it cannot directly be added to food, it can be used as a preservative or cleaning agent during production of packaging materials, processing equipment and food additives. Phenoxyethanol helps prevent microorganisms from growing on packaging materials which extends their shelf life; for cleaning and disinfection processes on equipment it effectively removes dirt and microbial residues on equipment surfaces to ensure hygiene and safety during food production processes.
Phenoxyethanol has many unique applications in aquaculture. It can act as an anesthetic for fish during transportation, induced spawning, and other operations, helping farmers ease into performing related operations more easily and improve efficiency and quality of aquaculture.
The product advantage of Phenoxyethanol is first reflected in the dimension of safety. Compared with traditional preservatives, its sensitization probability is reduced by about 60%, and clinical tests show that the incidence of contact dermatitis is less than 0.03%. This high safety stems from the stability of the molecular structure. The combination of the benzene ring and the ethylene glycol group makes it difficult to be decomposed by skin metabolic enzymes, thereby avoiding the production of irritating byproducts. At the same time, its broad-spectrum antibacterial properties cover more than 200 common microorganisms, and its resistance develops slowly, showing unique value in the field of medical device sterilization. Experimental data show that after five years of continuous use, the sensitivity of pathogens to Phenoxyethanol has only decreased by 2.3%.
Physical and chemical stability is another core competitiveness of this product. In the pH range of 3-10, the chemical structure of Phenoxyethanol remains intact, and the antibacterial activity fluctuates by less than 5%. This feature enables it to adapt to various formulation systems. The temperature stability test shows that the retention rate of active ingredients after heating at 150°C for 24 hours is still 98.7%, far exceeding the average level of similar products. Compatibility tests with common surfactants and oil ingredients have proven that it will not produce precipitation or stratification in complex formulas, which is of key significance for the development of high-end cosmetics.
From an environmental perspective, the biodegradation half-life of Phenoxyethanol is only 7-10 days, and the conventional process of sewage treatment plants can remove more than 95% of the residue. The life cycle analysis report pointed out that the carbon footprint of its production process is 34% lower than that of similar preservatives, and the water consumption per ton of product is reduced by 2.8 cubic meters. In terms of economy, although the unit cost is slightly higher than that of traditional preservatives, the overall cost-effectiveness is significantly improved because its concentration can be reduced by 30%-50%.
Market feedback data reveals its potential for continued growth. In the past five years, the average annual growth rate of global demand has reached 6.7%, of which the Asia-Pacific region has contributed 58% of the increase. The terminal product survey shows that the repurchase rate of cosmetics containing Phenoxyethanol is 12 percentage points higher than the industry average, which is closely related to its good user experience. Industry forecasts show that as national regulations strengthen restrictions on traditional preservatives, Phenoxyethanol’s market share is expected to exceed US$4.5 billion by 2028. The synergistic effect of technological innovation and market demand is driving this classic compound to a new life.
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Related References:
chemicalbook-Phenoxyethanol
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As an experienced Phenoxyethanol manufacturer and supplier, Look Chemical is committed to producing and selling high quality products.
We cooperate and trade with 6000+ factories around the world, and our high-quality products and excellent services make us enjoy a high reputation internationally.
As Phenoxyethanol CAS 122-99-6 supplier, Look Chemical provides supply chain solutions to partners and customers in a wide range of industries. We offer competitive pricing and quality products.
If you have a demand for this product, please contact our company’s sales staff, we will provide you with a solution in the shortest time.
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1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
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