Methoxypolyethylene Glycols CAS 9004-74-4

Methoxypolyethylene Glycols CAS 9004-74-4

Methoxypolyethylene Glycols CAS 9004-74-4 With Top Selling

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Name: Methoxypolyethylene Glycols

CAS: 9004-74-4

MOQ: 1KG

Directory Guidance on Methoxypolyethylene Glycols

Product Introduction:

Methoxypolyethylene glycol (MPEG)is a chemical substance formed by the reaction of polyethylene glycol (PEG) with methylated groups. Its molecule contains one ethylene glycol unit and one methylating group, structurally intermediate between polyethylene glycol and methanol. Due to its good water solubility and biocompatibility, Methoxypolyethylene Glycols are widely used in drug delivery systems, cosmetics, and biomedicine.

In the field of pharmaceuticals, Methoxypolyethylene Glycols are commonly used to prepare drug carriers, which can effectively improve the solubility, stability, and bioavailability of drugs. Its water-soluble characteristics make it have good solubility in the body, and by prolonging the half-life of the drug in the body, it reduces the side effects of the drug and enhances its efficacy. In addition, the surface hydrophilicity of Methoxypolyethylene Glycols is strong, which helps improve the permeability and absorption rate of drugs.

In the cosmetics industry, Methoxypolyethylene Glycols are commonly used as moisturizers, moisturizers, and solvents. It can form a protective film, keep moisture and improve the softness of the skin, so it is widely used in skin creams, lotion and other personal care products.

Due to its high safety and biocompatibility, Methoxypolyethylene Glycols have also been used in coatings for medical devices, medical packaging materials, and other materials that come into contact with the human body, showing promising application prospects. However, with the increasing emphasis on environmental protection, some studies have begun to focus on the environmental degradation of Methoxypolyethylene Glycols, so there may be more alternative materials emerging in the future.

Basic Info:

Chemical Structure

Melting point 60-64 °C
Boiling point >200°C/760mmHg
density 1.094 g/mL at 25 °C
vapor density >1 (vs air)
vapor pressure 0.05 mm Hg ( 20 °C)
refractive index n20/D 1.459
Fp 268 °C

Nature and Specifications:

What Are The Uses of Methoxypolyethylene Glycols

Product service:

Methoxypolyethylene glycol is an important chemical substance that has been widely used in various fields due to its unique molecular structure, excellent water solubility, biocompatibility, and chemical stability. Here are its applications in various fields:

1. Drug delivery and formulation field
Methoxypolyethylene glycols are widely used in pharmaceutical formulations, especially in drug delivery systems (DDS). Due to its good water solubility and biocompatibility, MPEG is often used as a drug carrier to enhance the solubility, bioavailability, and stability of drugs. Specific applications include:
① Drug sustained release: Methoxypolyethylene glycols can achieve sustained or controlled release by changing the release rate of the drug. For example, as a polymer matrix, MPEG can control the release of drug molecules, reduce the frequency of administration, and improve patient compliance.
② Improving drug solubility: For drugs with poor water solubility, MPEG can significantly enhance their solubility by forming solutions or colloids, thereby improving their bioavailability.
③ PEGylation modification: PEGylation is a common method of drug modification, which involves grafting MPEG onto drug molecules to reduce their immunogenicity, prolong their half-life, and minimize their toxic side effects. This technology is widely used in the development of anti-cancer drugs, antibody drugs, and vaccines.
④ Nano drug system: MPEG is commonly used for surface modification of nanoparticles to improve the biocompatibility and cycle time of nano drug systems, and enhance drug targeting.

2. Cosmetics and personal care products
The application of Methoxypolyethylene Glycols in cosmetics and personal care products is mainly reflected in their moisturizing, lubricating, and dissolving effects. Specific applications include:
① Moisturizing agent: Methoxypolyethylene Glycols, as an excellent hydrophilic ingredient, can help the skin retain moisture, prevent water loss, and keep the skin soft and smooth. It is commonly used in skin cream, lotion, essence liquid, facial mask and other products.
② Solvent: MPEG can be used as a solvent to dissolve oil soluble components in cosmetic formulations and improve their stability. It is often used in liquid skin care products, perfume and cosmetics to increase the uniformity and comfort of products.
③ Emulsifier: Due to the balance of hydrophilicity and lipophilicity of MPEG, it can help water and oil phases form stable emulsions in lotion, which can be used in face cream, shampoo, conditioner and other products.
④ Alternative preservatives: MPEG can also have a preservative effect to some extent, helping to extend the shelf life of cosmetics and reduce the use of chemical preservatives.

3. Biomedical field
In the field of biomedicine, Methoxypolyethylene Glycols are widely used in various applications, especially in biomedical devices, drug delivery systems, etc., due to their excellent biocompatibility and low toxicity.
① Biomedical devices: MPEG can be used to coat the surface of medical devices, improve their biocompatibility, and reduce immune and inflammatory reactions that occur when the devices come into contact with the human body. For example, some implantable medical devices, such as catheters and stents, often use PEGylated materials for surface treatment to reduce thrombus formation and enhance cell affinity.
② Biopharmaceuticals: PEGylation technology can improve the stability and solubility of protein drugs, vaccines, and other biopharmaceutical products. For example, MPEG is used to synthesize certain recombinant proteins and antibody drugs, which can enhance their stability and prolong their half-life in vivo.

4. Environmental and Materials Science
Methoxypolyethylene glycols also have certain potential applications in the fields of environmental protection and materials science.
① Water treatment: As a hydrophilic molecule, MPEG can effectively adsorb harmful substances in water, help remove oil stains or other pollutants in water, and is applied in the fields of water treatment and environmental purification.
② Polymer materials: Due to their good solubility and stability, Methoxypolyethylene Glycols are often used as modifiers for polymer materials and play an important role in the preparation of some polymer films, coatings, and adhesives. For example, MPEG can be used to manufacture biodegradable plastic materials and enhance their flexibility and biodegradability.

5. Food industry
Methoxypolyethylene glycols are relatively less commonly used in the food industry, but they are also used as food additives, food packaging materials, and other applications.
① Food additive: MPEG can be used in food additives as a solvent or moisturizer to improve the texture and taste of food. For example, as a carrier for certain sweeteners and anti caking agents, it helps to evenly disperse other ingredients.
② Food packaging: MPEG can also be used as a coating for food packaging materials, improving the stability and sealing performance of packaging materials and extending the shelf life of food.

Methoxypolyethylene glycols have been widely used in various fields, especially in drug delivery, biomedicine, cosmetics, environmental protection, etc., due to their unique chemical properties and biocompatibility. With the continuous development of technology, the application prospects of MPEG are still very broad, especially in the fields of precision drug delivery, nanotechnology, biomedical and green materials.

Safety Precautions of Methoxypolyethylene Glycols

 

Methoxypolyethylene glycols have the following characteristics in terms of safety:

Low toxicity: Methoxypolyethylene glycol itself is considered non-toxic and non irritating, and is widely used in various pharmaceutical formulations. Low molecular weight polyethylene glycol is relatively toxic, but overall, the toxicity of diols is quite low.

Local application: In local application, especially mucosal administration, MPEG may cause irritating pain.

Oral effects: High doses of oral administration of MPEG may cause digestive system problems such as diarrhea.

• Use in injections: The maximum concentration of polyethylene glycol 300 in injections is approximately 30% (V/V), and concentrations exceeding 40% (V/V) may cause hemolysis.

Environmental impact: Generally not harmful to water, but materials should not be discharged into the surrounding environment without government permission.

Stability: Methoxypolyethylene glycols are stable at room temperature and pressure, and should avoid exposure to light, open flames, and high temperatures.

• Safety instructions: According to safety information, the safety instructions for MPEG are 24/25-22, and WGK Germany has rated it as 3, which means it belongs to low-risk substances in Germany’s environmental classification.

In summary, Methoxypolyethylene Glycols are considered safe under normal usage conditions, but may cause some adverse reactions under specific conditions or when used at high doses. Therefore, appropriate safety measures and guiding principles should be followed when using.

 

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Product picture:

Methoxypolyethylene Glycols CAS 9004-74-4
Methoxypolyethylene Glycols CAS 9004-74-4
Methoxypolyethylene Glycols CAS 9004-74-4

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Methoxypolyethylene Glycols CAS 9004-74-4
Methoxypolyethylene Glycols CAS 9004-74-4

Related References:

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Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

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